Guitarist Peter Buck commented on the making of the track saying "'Everybody Hurts' is similar to 'Man on the Moon'. Bill brought it in, and it was a one-minute long country-and-western song. It didn't have a chorus or a bridge. It had the verse. . . it kind of went around and around, and he was strumming it. We went through about four different ideas and how to approach it and eventually came to that Stax, Otis Redding, "Pain in My Heart" kind of vibe. I'm not sure if Michael would have copped that reference, but to a lot of our fans it was a Staxxy-type thing. It took us forever to figure out the arrangement and who was going to play what, and then Bill ended up not playing on the original track. It was me and Mike and a drum machine. And then we all overdubbed. "